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Although the 2xAV Plug-In for RealPlayer works on Microsoft Windows Vista, it is not yet officially supported. To use the 2xAV Plug-In for RealPlayer on Windows Vista, you must be running 2xAV Plug-In version 3.11 or later.

The 2xAV Plug-In for Microsoft Windows Media Player is not supported on Vista. If you need to view Windows Media Content while running Vista, you must install RealPlayer 10.5 (not RealPlayer 11) and set RealPlayer as the default player for Windows Media content. See Where can I find previous versions of RealPlayer? to find these earlier versions.

2xAV is loaded by the RealPlayer core audio architecture. The RealPlayer core audio architecture is itself a RealPlayer Plug-In and is not loaded by RealPlayer until the media format has been determined, which is why the 2xAV menu choice will not appear in the RealPlayer tools menu until you select your media file. For most of the media formats that RealPlayer is capable of playing, RealPlayer will load the default audio architecture (which then loads 2xAV). However, for some media formats, such as MPEG4 and Windows Media (WMA, WMV), RealPlayer must use a different architecture and thus never loads 2xAV. For example, for the Windows Media format, RealPlayer loads the Windows Media Directshow architecture to decode and simply wraps the RealPlayer user interface around the presentation. In this case, if you have installed a licensed copy of 2xAV for Windows Media Player, then you would still get the 2xAV functionality since 2xAV for Windows Media Player is loaded by the Windows Media Directshow architecture.