As of Chrome v24.0.1312.57 released on January 30th, Chrome has changed the way it handles the audio buffer size and this has caused audio quality problems for many users, even those not using MySpeed.  Read more to see some options.

You can see on this Issue Report at the Chrome developers site that other users are having audio quality problems even without MySpeed:

https://code.google.com/p/chromium/issues/detail?id=161307 (Scroll to the bottom)

It also affects Chrome's PepperFlash player so another option is to disable PepperFlash by following the instructions here:

Disable PepperFlash in Chrome

Another work around is to use a command line option to tell Chrome to use a different Audio Buffer size.  The command line option would be: "--audio-buffer-size=1992". 

For Windows users, I suggest that you make a 2nd Chrome Icon on your desktop and add this --audio-buffer-size option to the command line for that icon.

1. Open the Start menu and find Chrome in the start menu.
2. Right-click and hold on the Chrome icon and drag it to the Desktop to make a Copy
3. Right-click on the Chrome icon that is now on the Desktop and select Properties
4. Click in the "Target" box, and press the "End" key on the keyboard to move the cursor to the end of the line.
5. Add a space and then add this text (copy and paste with Ctrl-C and Ctrl-V):
6.       --audio-buffer-size=1992
7. Now when you click this new icon on the desktop, you'll launch Chrome we a larger buffer size and that helps with the quality issue.
8. Increase that number in increments of 400 (approximately 10ms of audio) to try different buffer sizes.

Applies to: MySpeed for Windows and MySpeed for Mac

Operatin System: Windows and OS X

Browser: Google Chrome